Bonne Santé Liposome: Liposomal Magnesium+ Optinerve ® - 250ml
Liposomal Magnesium for healthy muscles, nerves and heart
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Contains: (per 5 ml) 31.25 mg Magnesium; 0.8 mg Zinc; 4.55 μg Selenium; 3.65 μg Chromium; 25 mg Taurine.
Suggested dosage: 2 x 5 ml directly in mouth or glass of water or juice, unless otherwise advised by a healthcare professional. Do not exceed recommended dosage.
Ingredients: Magnesium bisglycinate (10% Mg); Zinc glycinate (20% Zn); L-Selenomethionine (40% Se); Chromium picolinate (12.1% Cr); Taurine; lecithin (Non-GMO SOY) - emulsifier; glycerol - humectant; ethanol < 2.7%; xylitol – sweetener; mint aroma – flavouring; natural vitamin E (as d-alpha tocopherol) - antioxidant; potassium sorbate - preservative; purified water.
Recommended serving size: 5 ml
Servings per bottle: 50
Storage: Store cool and dry. When opened store in refrigerator and finish within 2 months.
Product description PDF: View Here
- 250ml Magnesium
- Liposomal magnesium for improved bioavailability and absorption
- A unique magnesium composition with other minerals such as zinc, selenium, chrome and taurine
- Available in mint flavour
- Non-GMO product
- Measuring cup included
- Resealable screw top lid
- Relieves muscle cramps
- Helps in making healthy bones
- Maintains heart health
- Reduces PMS symptoms
- Relieves stress and promotes sound sleep
- Protects against radiation damage
- Helpful in migraines
- Improves asthma symptoms
Magnesium plays a very important role in nearly every process in the cell. It serves as a co-factor in more than 600 enzymatic reactions, including: 
- Energy production
- DNA and protein synthesis
- DNA repair
- Regulating calcium levels
- Glucose metabolism
- Regulating hormones and neurotransmitters
- Healthy functioning of nerves and muscles
- Vitamin D metabolism
- Regulating blood pressure
- Glutathione synthesis
Abnormal accumulation of calcium in kidneys, arteries, bones and intestines can also result in all kinds of health complications – including the formation of kidney stones, formation of plaque within arteries, osteoporosis and constipation. And all this happens when you have inadequate magnesium levels in the body.
1. Helps in ATP synthesis, improves energy levels
Magnesium deficiency often results in low energy levels and fatigue. There is a good reason for it. Magnesium is an important part of the ‘team of nutrients’ that your body needs to create energy.
- Helps in the production of ATP, the main source of energy for cells.
- Activates ATP so that it can be used by the cells. (ATP binds to magnesium ions to become activated)
By keeping excess calcium out of the cells, magnesium helps muscles to relax. Sore muscles, leg cramps and Charlie horses are often the most common signs of magnesium deficiency. It also reduces nerve pain by preventing excessive stimulation of NDMA, a neurotransmitter associated with pain mechanisms.
- Relaxes muscles
- Reduces pain in muscles and nerves
- Provides relief in painful muscle spasms and leg cramps, and chronic fatigue syndrome
People with a low magnesium level often develop symptoms such as frayed nerves, chronic fatigue, wide-spread pain, depression, anxiety and disturbed sleep. Magnesium helps in improving all of these symptoms and calms nerves and reduces stress, mostly by balancing neurotransmitters (hormones) associated with sleep, mood and anxiety.
- Regulates calcium and glutamate, that causes excitability in nerves
- Increases GABA, a hormone that helps lower anxiety levels and helps you calm down
- Regulates stress hormones, such as cortisol
- Helps in the production of serotonin, a hormone that regulates sleep and mood, among other things.
4. Reduces risk of heart disease
Studies show that magnesium deficiency is associated with an increased risk of high blood pressure, angina, atherosclerosis, congestive heart failure and heart attack.  Magnesium helps in cutting down your risk of developing cardiovascular disease through a number of actions:
- Lowers blood pressure by relaxing blood vessels
- Prevents plaque formation by preventing calcium build-up in arteries. (Atherosclerosis is a risk factor for heart attack or stroke.)
- Prevents clotting
- Reduces stress and anxiety
- Lowers inflammation, an underlying mechanism for heart disease
Maintaining a healthy magnesium status is important for your bone health. Studies show that it:
- Helps in improving bone density
- Lowers risk of osteoporosis in women after menopause
- Lowers the risk of fractures 
- Magnesium influences bone health through various mechanisms: 
- Helps in calcium absorption and utilization
- Converts vitamin D into its biologically active form.
- Activates enzymes involved in vitamin D metabolism
- Stimulates calcitonin, a hormone produced by the thyroid gland. Calcitonin draws extra calcium from the circulation, kidneys, muscles and blood vessels and send it to bones. This not only improves bone mineral density but also lowers the risk of other conditions related to calcium build-up.
Magnesium deficiency increases the risk of metabolic syndrome, a group of disorders that make you highly vulnerable to developing type 2 diabetes and heart disease. This is yet another way magnesium plays a role in reducing heart disease risk. Magnesium may also be helpful for pre-diabetics as it appears to offset the risk of diabetes in people with high risk. 
Getting sufficient magnesium is very important in people with type 2 diabetes. Firstly, you need magnesium for healthy glucose metabolism. Secondly, higher than normal blood glucose and insulin increases magnesium loss through urine. This further reduces magnesium levels.
- Improves insulin sensitivity
- Improves glucose metabolism and lowers blood sugar
- Improves oxidative stress, and inflammation, associated with reduced insulin sensitivity 
- Provides relief in migraine and tension headaches
- Improves many PMS symptoms such as pain, contractions, migraines and depression
- Protects from the damage caused by ionizing radiation
- Ensures proper functioning of proteins or enzymes used in DNA synthesis and repair
- Required in various detoxification pathways
- Helps in glutathione synthesis (a powerful endogenous antioxidant and even more potent detoxifier).
- Improves exercise performance (due to its role in energy metabolism, muscle functions and heart functions).
- Improves asthma symptoms and prevents flare-ups (as it reduces inflammation, improves pulmonary functions and relaxes airways).
- Gets rid of constipation
Bonne Sante Liposome Magnesium
The Magnesium+ Optinerve ® is one of the few magnesium supplements that can boost your cellular magnesium levels without causing diarrhea. Oral magnesium supplements, available in powder or tablet form, work as laxatives. You can’t take high amounts without the risk of bloating, abdominal cramps and diarrhea. With Liposomal magnesium supplements, you can be assured of no such side effects while achieving better absorption by cells.
The concentration of magnesium in our Bonne Sante Liposome product per ml is lower than in traditional products, but several product characteristics assure better absorption of the magnesium in our product compared to traditional products. These are:
- Most significant is the fact that our product offers true liposomal enhancing absorption
- Our unique and patented Optinerve recipe: the combination with the other minerals is proven to increase absorption itself
- We use magnesium bisglycinate: All mineral are absorbed in the body by the same mineral absorption pathway. This means that when zinc is absorbed, that particular system is busy and cannot absorb magnesium. For that reason we use magnesium bisglycinate which does not use the mineral complex absorption pathway, but the amino acid absorption pathway (it contains 2 glycine molecules, which are amino-acids)
By a combination of these factors, we estimate the absorption of our product to be ~10x better than traditional products.
- Baaij et al. Magnesium in man: implications for health and disease. Physiol Rev. 2015
- Eby et al. GA, Eby KL. Magnesium for treatment-resistant depression: a review and hypothesis. Medical Hypothesis. 2010
- Murck H. Ketamine, magnesium and major depression--from pharmacology to pathophysiology and back. Journal of Psychiatric Research. 2013.
- DiNicolantonio et al. Subclinical magnesium deficiency: a principal driver of cardiovascular disease and a public health crisis. Open Heart. 2018
- Kunutsor et al. Low serum magnesium levels are associated with increased risk of fractures: a long-term prospective cohort study. European Journal of Epidemiology. 2017
- Castiglioni et al. Magnesium and osteoporosis: current state of knowledge and future research directions. Nutrients. 2013
- Hruby et al. Higher magnesium intake reduces risk of impaired glucose and insulin metabolism, and progression from prediabetes to diabetes in middle-aged Americans. Diabetes Care 2013
- Barbagallo et al. Magnesium and type 2 diabetes. World J Diabetes. 2015